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Climate Change 2022 – Impacts, Adaptation and Vulnerability

Intergovernmental Panel on Climate Change 2023

The Working Group II contribution to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC) provides a comprehensive assessment of the scientific literature relevant to climate change impacts...

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Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

Kristina E. Rudd, Sarah Charlotte Johnson, Kareha M Agesa, Katya Anne Shackelford, Derrick Tsoi, Daniel Kievlan, Danny V. Colombara, Kevin S Ikuta, Niranjan Kissoon, Simon Finfer, Carolin Fleischmann-Struzek, Flávia Ribeiro Machado, Konrad Reinhart, Kathy Rowan, Christopher W. Seymour, R. Scott Watson, T. Eoin West, Maria de Fátima Marinho de Souza, Simon I Hay, Rafael Lozano, Alan D López, Derek C. Angus, Christopher J L Murray, Mohsen Naghavi 2020

BackgroundSepsis is life-threatening organ dysfunction due to a dysregulated host response to infection. It is considered a major cause of health loss, but data for the global burden of sepsis are limited. As a syndrome...

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2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Scott M. Grundy, Neil J. Stone, Alison Bailey, Craig Beam, Kim K. Birtcher, Roger S. Blumenthal, Lynne T. Braun, Sarah D. de Ferranti, Joseph Faiella-Tommasino, Daniel E. Forman, Ronald Goldberg, Paul A. Heidenreich, Mark A. Hlatky, Daniel W. Jones, Donald M. Lloyd‐Jones, Nuria Lopez-Pajares, Chiadi E. Ndumele, Carl E. Orringer, Carmen Peralta, Joseph J. Saseen, Sidney C. Smith, Laurence S. Sperling, Salim S. Virani, Joseph Yeboah 2019
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The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application

Stephen A. Lauer, Kyra H. Grantz, Qifang Bi, Forrest K. Jones, Qulu Zheng, Hannah R. Meredith, Andrew S. Azman, Nicholas G Reich, Justin Lessler 2020

A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in China in December 2019. There is limited support for many of its key epidemiologic features, including the incuba...

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Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

Jun Lan, Jiwan Ge, Jinfang Yu, Sisi Shan, Huan Zhou, Shilong Fan, Qi Zhang, Xuanling Shi, Qisheng Wang, Linqi Zhang, Xinquan Wang 2020

A new and highly pathogenic coronavirus (severe acute respiratory syndrome coronavirus-2, SARS-CoV-2) caused an outbreak in Wuhan city, Hubei province, China, starting from December 2019 that quickly spread nationwide an...

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2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes

Juhani Knuuti, William Wijns, Antti Saraste, Davide Capodanno, Emanuele Barbato, Christian Funck‐Brentano, Eva Prescott, Robert F. Storey, Christi Deaton, Thomas Cuisset, Stefan Agewall, Kenneth Dickstein, Thor Edvardsen, Javier Escaned, Bernard J. Gersh, Pavel Svítil, Martine Gilard, David Hasdai, Róbert Hatala, Felix Mahfoud, Josep Masip, Claudio Muneretto, Marco Valgimigli, Stephan Achenbach, Jeroen J. Bax, Franz-Josef Neumann, Udo Sechtem, Adrian Banning, Nikolaos Bonaros, Héctor Bueno, Raffaele Bugiardini, Alaide Chieffo, Filippo Crea, Martin Czerny, Victoria Delgado, Paul Dendale, Frank A. Flachskampf, H. Gohlke, Erik Lerkevang Grove, Stefan James, Demosthenes G. Katritsis, Ulf Landmesser, Maddalena Lettino, Christian M. Matter, Hendrik M. Nathoe, Alexander Niessner, Carlo Patrono, Anna Sonia Petronio, S. Pettersen, Raffaele Piccolo, Massimo Piepoli, Bogdan A Popescu, Lorenz Räber, Dimitrios Richter, Marco Roffi, Franz Xaver Roithinger, Е. V. Shlyakhto, Dirk Sibbing, Sigmund Silber, Iain Simpson, Miguel Sousa‐Uva, Panos Vardas, Adam Witkowski, Jose Luis Zamorano, Stephan Achenbach, Stefan Agewall, Emanuele Barbato, Jeroen J. Bax, Davide Capodanno, Thomas Cuisset, Christi Deaton, Kenneth Dickstein, Thor Edvardsen, Javier Escaned, Christian Funck‐Brentano, Bernard J. Gersh, Martine Gilard, David Hasdai, Róbert Hatala, Felix Mahfoud, Josep Masip, Claudio Muneretto, Eva Prescott, Antti Saraste, Robert F. Storey, Pavel Svítil, Marco Valgimigli, Stephan Windecker, Victor Aboyans, Colin Baigent, Jean-Philippe Collet, Veronica Dean, Victoria Delgado, Donna Fitzsimons, Chris P Gale, Diederick E. Grobbee, Sigrun Halvorsen, Gerhard Hindricks, Bernard Iung, Peter Jüni 2019

Coronary artery disease (CAD) is a pathological process characterized by atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive. This process can be modified by lifestyle a...

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Endothelial cell infection and endotheliitis in COVID-19

Zsuzsanna Varga, Andreas J. Flammer, Peter Steiger, Martina Haberecker, Rea Andermatt, Annelies S. Zinkernagel, Mandeep R. Mehra, Reto A. Schuepbach, Frank Ruschitzka, Holger Moch 2020

Cardiovascular complications are rapidly emerging as a key threat in coronavirus disease 2019 (COVID-19) in addition to respiratory disease. The mechanisms underlying the disproportionate effect of severe acute respirato...