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The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets

Damian Szklarczyk, Annika L Gable, Katerina Nastou, David Lyon, Rebecca Kirsch, Sampo Pyysalo, Nadezhda T. Doncheva, Marc Legeay, Tao Fang, Peer Bork, Lars Juhl Jensen, Christian von Mering • 2020

Cellular life depends on a complex web of functional associations between biomolecules. Among these associations, protein–protein interactions are particularly important due to their versatility, specificity and adaptabi...

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2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk

François Mach, Colin Baigent, Alberico L. Catapano, Konstantinos C. Koskinas, Manuela Casula, Lina Badimón, M. John Chapman, Guy G De Backer, Victoria Delgado, Brian A. Ference, Ian M Graham, Alison Halliday, Ulf Landmesser, Borislava Mihaylova, Terje R. Pedersen, Gabriele Riccardi, Dimitrios J Richter, Marc S. Sabatine, Marja‐Riitta Taskinen, Lale Tokgozoglu, Olov Wiklund, Christian Mueller, Heinz Drexel, Victor Aboyans, Alberto Corsini, Wolfram Doehner, Michel Farnier, Bruna Gigante, Meral Kayıkçıoğlu, Goran Krstačić, Ekaterini Lambrinou, Basil S. Lewis, Josep Masip, Philippe Moulin, Steffen E. Petersen, Anna Sonia Petronio, Massimo Piepoli, Xavier Pintó, Lorenz Räber, Kausik K. Ray, Željko Reiner, Walter F. Riesen, Marco Roffi, Jean-Paul Schmid, Е. V. Shlyakhto, Iain A Simpson, Erik S.G. Stroes, Isabella Sudano, Alexandros D. Tselepis, Margus Viigimaa, Cécile Vindis, Alexander Vonbank, Michal Vrablik, Mislav Vrsalović, José Luis Zamorano, Jean-Philippe Collet, Konstantinos C. Koskinas, Manuela Casula, Lina Badimón, M. John Chapman, Guy G De Backer, Victoria Delgado, Brian A. Ference, Ian M Graham, Alison Halliday, Ulf Landmesser, Borislava Mihaylova, Terje R. Pedersen, Gabriele Riccardi, Dimitrios J Richter, Marc S. Sabatine, Marja‐Riitta Taskinen, Lale Tokgozoglu, Olov Wiklund, Stephan Windecker, Victor Aboyans, Colin Baigent, Jean-Philippe Collet, Verónica Dean, Victoria Delgado, Donna Fitzsimons, Chris P Gale, Diederick E. Grobbee, Sigrun Halvorsen, Gerhard Hindricks, Bernard Iung, Peter Jüni, Hugo A. Katus, Ulf Landmesser, Christophe Leclercq, Maddalena Lettino, Basil S Lewis, Bela Merkely, Christian Mueller, Steffen E. Petersen, Anna Sonia Petronio, Dimitrios J Richter, Marco Roffi, Е. V. Shlyakhto, Iain A Simpson • 2019

The ESC/EAS Guidelines represent the views of the ESC and EAS, and were produced after careful consideration of the scientific and medical knowledge, and the evidence available at the time of their publication.The ESC an...

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The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

Alexander E. Gorbalenya, Susan C. Baker, Ralph S. Baric, Raoul J. de Groot, Christian Drosten, Anastasia Gulyaeva, Bart L. Haagmans, Chris Lauber, A. M. Leontovich, Benjamin W. Neuman, Dmitry Penzar, Stanley Perlman, Leo L. M. Poon, Dmitry V. Samborskiy, Igor A. Sidorov, Isabel Sola, John Ziebuhr • 2020

The present outbreak of a coronavirus-associated acute respiratory disease called coronavirus disease 19 (COVID-19) is the third documented spillover of an animal coronavirus to humans in only two decades that has result...

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IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045

Hong Sun, Pouya Saeedi, Suvi Karuranga, Moritz Pinkepank, Katherine Ogurtsova, Bruce Bartholow Duncan, Caroline Stein, Abdul Basit, Juliana C.N. Chan, Jean Claude Mbanya, Meda E. Pavkov, Ambady Ramachandaran, Sarah H. Wild, Steven James, William H. Herman, Ping Zhang, Christian Bommer, Shihchen Kuo, Edward J. Boyko, Dianna J. Magliano • 2021
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Remdesivir for the Treatment of Covid-19 — Final Report

John H. Beigel, Kay M Tomashek, Lori E. Dodd, Aneesh K. Mehta, Barry S. Zingman, André C. Kalil, Elizabeth Hohmann, Helen Y. Chu, Annie Luetkemeyer, Susan Kline, Diego López de Castilla, Robert W. Finberg, Kerry Dierberg, Victor F. Tapson, Lanny Hsieh, Thomas F. Patterson, Roger Paredes, Daniel A Sweeney, William R. Short, Giota Touloumi, David Chien Lye, Norio Ohmagari, Myoung‐don Oh, Guillermo M. Ruiz‐Palacios, Thomas Benfield, Gerd Fätkenheuer, Mark G. Kortepeter, Robert L. Atmar, C. Buddy Creech, Jens Lundgren, Abdel G. Babiker, Sarah Pett, James D. Neaton, Timothy Burgess, Tyler Bonnett, Michelle Green, Mat Makowski, Anu Osinusi, Seema Nayak, H. Clifford Lane • 2020

Although several therapeutic agents have been evaluated for the treatment of coronavirus disease 2019 (Covid-19), no antiviral agents have yet been shown to be efficacious. We conducted a double-blind, randomized, placeb...

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Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Christopher J L Murray, Aleksandr Y. Aravkin, Peng Zheng, Cristiana Abbafati, Kaja Abbas, Mohsen Abbasi‐Kangevari, Foad Abd-Allah, Ahmed Abdelalim, Mohammad Abdollahi, Ibrahim Abdollahpour, Kedir Hussein Abegaz, Hassan Abolhassani, Victor Aboyans, Lucas Guimarães Abreu, Michael R.M. Abrigo, Ahmed Abualhasan, Laith J. Abu‐Raddad, Abdelrahman Ibrahim Abushouk, Maryam Adabi, Victor Adekanmbi, Abiodun M. Adeoye, Olatunji Adetokunboh, Davoud Adham, Shailesh M Advani, Gina Agarwal, Seyed Mohammad Kazem Aghamir, Anurag Agrawal, Tauseef Ahmad, Keivan Ahmadi, Mehdi Ahmadi, Hamid Ahmadieh, Muktar Beshir Ahmed, Temesgen Yihunie Akalu, Rufus Akinyemi, Tomi Akinyemiju, Blessing Akombi-Inyang, Chisom Joyqueenet Akunna, Fares Alahdab, Ziyad Al‐Aly, Khurshid Alam, Shazia Alam, Shazia Alam, Fahad Alanezi, Turki M Alanzi, Biresaw Wassihun, Khalid F. AlHabib, Muhammad Ali, Saqib Ali, Gianfranco Alicandro, Cyrus Alinia, Vahid Alipour, Hesam Alizade, Syed Mohamed Aljunid, François Alla, Peter Allebeck, Amir Almasi‐Hashiani, Hesham M. Al‐Mekhlafi, Jordi Alonso, Khalid A Altirkawi, Mostafa Amini‐Rarani, Fatemeh Amiri, Dickson A Amugsi, Robert Ancuceanu, Deanna Anderlini, Jason A Anderson, Cătălina Liliana Andrei, Tudorel Andrei, Colin Angus, Mina Anjomshoa, Fereshteh Ansari, Alireza Ansari-Moghaddam, Ippazio Cosimo Antonazzo, Carl Abelardo T Antonio, Catherine M Antony, Ernoiz Antriyandarti, Davood Anvari, Razique Anwer, Seth Christopher Yaw Appiah, Jalal Arabloo, Morteza Arab‐Zozani, Filippo Ariani, Bahram Armoon, Johan Ärnlöv, Afsaneh Arzani, Mehran Asadi-Aliabadi, Ali A. Asadi‐Pooya, Charlie Ashbaugh, Michael Assmus, Zahra Atafar, Desta Debalkie Atnafu, Maha Atout, Floriane Ausloos, Marcel Ausloos, Beatriz Paulina Ayala Quintanilla, Getinet Ayano, Martin Amogre Ayanore, Samad Azari, Ghasem Azarian, Zelalem Nigussie Azene, Alaa Badawi • 2020

<h2>Summary</h2><h3>Background</h3> Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making pr...

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ColabFold: making protein folding accessible to all

Milot Mirdita, Konstantin Schütze, Yoshitaka Moriwaki, Lim Heo, Sergey Ovchinnikov, Martin Steinegger • 2022

Abstract ColabFold offers accelerated prediction of protein structures and complexes by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFold’s 40−60-fold faster search and optimized mod...

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Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019

Jianbo Lai, Simeng Ma, Ying Wang, Zhongxiang Cai, Jianbo Hu, Ning Wei, Jiang Wu, Hui Du, Tingting Chen, Ruiting Li, Huawei Tan, Lijun Kang, Lihua Yao, Manli Huang, Huafen Wang, Gaohua Wang, Zhongchun Liu, Shaohua Hu • 2020

<h3>Importance</h3> Health care workers exposed to coronavirus disease 2019 (COVID-19) could be psychologically stressed. <h3>Objective</h3> To assess the magnitude of mental health outcomes and associated factors among...

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Metodologi Penelitian Kualitatif

Muhammad Rizal Pahleviannur, Anita De Grave, Dani Nur Saputra, Dedi Mardianto, Debby Sinthania, Lis Hafrida, Vidriana Oktoviana Bano, Eko Edy Susanto, Ardhana Januar Mahardhani, Amruddin Amruddin, Mochamad Doddy Syahirul Alam, Mutia Lisya, Dasep Bayu Ahyar • 2022

Penelitian merupakan suatu proses penyelidikan yang dilakukan secara aktif, tekun, dan sistematis yang bertujuan untuk menemukan, menginterpretasikan, dan menemukan fakta-fakta yang baru, serta mengembangkan kesimpulan d...

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World Health Organization 2020 guidelines on physical activity and sedentary behaviour

Fiona Bull, Salih S Al-Ansari, Stuart Biddle, Katja Borodulin, Matthew P. Buman, Greet Cardon, Catherine Carty, Jean‐Philippe Chaput, Sébastien Chastin, Roger Chou, Paddy C. Dempsey, Loretta DiPietro, Ulf Ekelund, Joseph Firth, Christine M. Friedenreich, Leandro Martin Totaro Garcia, Muthoni Gichu, Russell Jago, Peter T. Katzmarzyk, Estelle V. Lambert, Michael F. Leitzmann, Karen Milton, Francisco B. Ortega, Chathuranga Ranasinghe, Emmanuel Stamatakis, Anne Tiedemann, Richard P. Troiano, Hidde P. van der Ploeg, Vicky Wari, Juana Willumsen • 2020

Objectives To describe new WHO 2020 guidelines on physical activity and sedentary behaviour. Methods The guidelines were developed in accordance with WHO protocols. An expert Guideline Development Group reviewed evidence...

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